Table 1.
Computed physicochemical parameters of candidate CPP sequences
| Name | Sequence | Hydrophobicity | Hydropathicity | Amphipathicity | Hydrophilicity | Charge |
|---|---|---|---|---|---|---|
| Ku70 | VPMLK | 0,03 | 0,88 | 0,73 | −0,32 | 1 |
| FGF | PIEVCMYREP | −0,15 | −0,29 | 0,50 | 0,11 | −1 |
| Pen | RQIKIWFQNRRMKWKK | −0,54 | −1,73 | 1,53 | 0,46 | 7 |
The selected sequences show marked differences in parameters relevant to cell penetration. This broad range of values is indicative of the diversity of selection from the wide field of known CPPs.