Table 3.
The correlation analysis between ectopic colonization bacteria and clinical features in alcohol dependence.
| FD age | FREW | FRED | ASD | AST | ALT | GGT | TBIL | HB | MCV | TSH | PACS | HAMD | BMI | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| gAlloprevotella | 0.41* | – | – | – | – | 0.36* | – | – | – | – | – | – | – | – |
| gEscherichia | – | – | – | – | −0.38** | – | – | – | – | – | – | – | – | – |
| gFusobacterium | – | – | – | – | – | – | – | – | – | 0.39* | – | – | – | – |
| gLachnospiracea_ incertae_sedis | – | −0.53** | – | – | −0.54** | −0.55** | −0.44* | – | – | – | −0.45* | – | – | – |
| gMegasphaera | – | – | – | −0.46* | – | – | – | – | – | – | – | −0.42* | −0.42* | −0.52** |
| gPrevotella | – | – | 0.47** | – | – | – | – | – | – | – | – | – | – | – |
| gSaccharibacteria | – | – | – | – | – | – | – | −0.39* | – | – | – | – | – | – |
| gStreptococcus | – | – | – | – | – | – | – | – | −0.37* | – | – | – | – | – |
AD, alcohol dependence; FD age, first Drinking age; FREW, frequency of drinking (weekly); FRED, frequency of drinking (daily); ASD, Average Standard Drinks per day; AST, aspartate aminotransferase; ALT, alanine transaminase; GGT, gamma-glutamyl transpeptidase; TBIL, total bilirubine; HB, hemoglobin; MCV, Mean Corpuscular Volume; TSH, Thyroid Stimulating Hormone; PACS, Pennsylvania Alcohol Craving Scale; HAMD, Hamilton Depression Scale; BMI, Body Mass Index; g relative aboundence of gut microbiota; *p < 0.05，**p < 0.01.