Table 2.

Content validity of PROMs^a: comparison of domains and subthemes in blogs with domains and items in PROMs.

Domain		Breast cancer	Rheumatoid arthritis	Parkinson disease	Diabetes mellitus
PROMs		BREAST-Q	HAQb	PDQ-39/PDQ-8c	WHO-5d
	Domains matching with subthemes blogs	Psychosocial well-being Sexual well-being Satisfaction with breast Satisfaction with nipple reconstruction Satisfaction with implants Breast animation deformity (implants) Physical well-being: chest Physical well-being: back and shoulder Adverse effects of radiation Satisfaction with information Satisfaction with information—breast surgeon Satisfaction with information—radiation oncologist Satisfaction with surgeon Satisfaction with office staff Satisfaction with medical team	Daily activities Physical health Pain Mobility	Activities of daily living Bodily discomfort Cognition Communication Emotional well-being Autonomy Social support Stigma	Feeling cheerful and in good spirits Feeling calm and relaxed Feeling active and vigorous Waking up fresh and rested
	Domains not matching with subthemes blogs	Satisfaction with back Physical well-being: abdomen Satisfaction with abdomen	Personal care	—e	Daily life filled with interesting things
PROMS		EORTC QLQ-BR45f	SF-36g	—	PHQ-9h
	Domainsi matching with subthemes blogs	Hair loss Upset by hair loss Ill or unwell feeling Hot flushes Headaches Feeling physically less attractive Feeling less feminine Dissatisfaction with body Worries about future health Pain in arm or shoulder Swollen breast Skin problems breast Pain in hands or feet Tingling in fingers or toes Problems with joints Stiffness in joints Pain in joints Aches or pain in bones Weight gain Problem of weight gain Satisfaction with cosmetic result of surgery Satisfaction with appearance of the skin of affected breast	Daily activities Physical health Psychological well-being Social activities Pain Fatigue Mobility General health		Feeling down, depressed, or hopeless Trouble falling or staying asleep, or sleeping too much Feeling tired or having little energy Poor appetite or overeating Feeling bad about oneself, or that one is a failure or let oneself or one’s family down Thoughts that one would be better off dead, or of hurting oneself
	Domainsi not matching with subthemes blogs	Dry mouth Different taste Painful, irritated, or watery eyes Problems looking at yourself naked Interest in sex Sexually active Sex is enjoyable Swollen arm or hand Problems raising or moving arm Excessive sweat Dizzy Soreness in mouth Reddening in mouth Aches or pain in muscles Dry vagina Discomfort in vagina Pain in vagina during sexual activity Dry vagina during sexual activity	Personal care		Little interest or pleasure in doing things Trouble concentrating on things Moving or speaking slowly, or being fidgety or restless
PROMs		EORTC QLQ-C30j	—	—	PAIDk
	Domainsi matching with subthemes blogs	Trouble with strenuous activities Trouble taking a long walk Trouble taking a short walk The need to stay in bed during the day Limited in doing work or other activities Limited in pursuing hobbies or leisure time activities Short of breath Feeling pain Need to rest Feeling weak Lack of appetite Feeling nauseated Having vomited Being constipated Having diarrhea Feeling tired Pain interfered with daily activities Difficulty concentrating Feeling tense Feeling irritable Feeling depressed Having difficulties remembering things Condition or treatment has interfered with family life Condition or treatment has interfered with social activities Condition or treatment caused financial difficulties			Feeling scared about living with diabetes Uncomfortable social situations related diabetes care Feeling depressed about living with diabetes Feeling overwhelmed by diabetes Worrying about low blood glucose reactions Feeling angry about living with Diabetes Feeling constantly concerned about food and eating Worrying about the future and the possibility of serious complications Feelings of guilt or anxiety about getting off track with diabetes management Not “accepting” diabetes Feeling unsatisfied with diabetes physician Feeling that diabetes is taking up too much mental and physical energy every day Feeling that friends and family are not supportive of diabetes management efforts Coping with complications of diabetes Feeling “burned-out” by the constant effort needed to manage diabetes
	Domainsi not matching with subthemes blogs	Need help with eating, dressing, washing or using the toilet Trouble sleeping			Not having clear and concrete goals for diabetes care Feeling discouraged with diabetes treatment plan Feelings of deprivation regarding food and meals Not knowing if mood or feelings are related to diabetes
Domains missing in all PROMs		Coping strategies Fertility or pregnancy support	Side effect drugs Flares Experiences treatment	Fulfilment Impact on social life Perceived quality of care Personality change Relationship Self-management Sleep disorder	—

^aPROM: patient-reported outcome measure.

^bHAQ: Health Assessment Questionnaire.

^cPDQ: Parkinson Disease Quality of Life Questionnaire.

^dWHO-5: 5-item World Health Organization Well-Being Index.

^e—: not available.

^fEORTC QLQ-BR45: European Organization for Research and Treatment of Cancer Quality of Life Questionnaire—Breast Cancer.

^gSF-36: Short-Form 36.

^hPHQ-9: 9-item Patient Health Questionnaire.

ⁱThe EORTC QLQ-C30, EORTC QLQ-BR45, WHO-5, PHQ-9, and PAID consist of lists of items not grouped into domains; therefore, the analyses for these 2 PROMs took place at the level of items.

^jEORTC QLQ-C30: EORTC Core Quality of Life Questionnaire.

^kPAID: Problem Areas in Diabetes.