TABLE 1.

Summary of CD and sedimentation equilibrium data for the gp41 model peptides

Peptide	[θ]222 value (10−3)a	Tm (°C)b	Molecular mass (kDa)c
N36(L6)C34	−26	79	NAd
N34(L6)C28	−31	70	24.4 (23.9)
N34(L5)C28	−31	68	24.9 (23.8)
N34(L10)C28	−29	67	26.6 (25.9)
N30(L6)C28	−20	39	NA

^a[θ]₂₂₂ was measured at 0°C at monomer peptide concentrations of 10 μM in 50 mM sodium phosphate (pH 7.0) and 150 mM NaCl (PBS). 

^bT_m was determined at monomer peptide concentrations of 10 μM. 

^cApparent molecular masses were determined with initial peptide concentrations of 10, 30, and 100 μM at 20°C. The expected value for a trimer is enclosed in parentheses. 

^dNA, not applicable. Data were fit to a single ideal species model plot of ln(absorbance) versus radial distance squared. Nonrandom residuals, indicative of aggregation or derivations from ideality, were observed.