Table 1.

Differential potential metabolites characterized in mice brains and change trends

Mode	No	Metabolite	Formula	m/z	RT (min)	ZSSG vs ZSS			ZSSG vs GABA
						Fold change	Trend		Fold change	Trend
ESI−	1	Aspartate	C4H7NO4	132.03	0.43	0.79	↓*		0.82	↓
	2	Inosine	C10H12N4O5	267.07	0.46	1.13	↑*		1.13	↑*
	3	Phenyllactic acid	C9H10O3	165.05	4.67	0.69	↓		0.49	↓*
	4	Uridine	C9H12N2O6	289.07	7.29	0.70	↓*		0.68	↓*
ESI+	5 6	2-monoolein 4-hydroxymethyl-3-methoxyphenoxyacetic acid	C21H40O4 C10H12O5	379.28 213.07	12.92 10.53	0.77 0.83	↓ ↓*		0.66 0.75	↓* ↓*
	7	Cis-gondoic acid	C20H38O2	328.32	11.86	0.61	↓*		0.58	↓*
	8	3-Hydroxydecanoyl carnitine	C17H33NO5	349.27	12.71	0.73	↓*		0.53	↓*
	9	Trans-2-hydroxycinnamic acid	C9H8O3	165.05	0.81	0.41	↓*		0.38	↓*
	10	Oxidized glutathione	C20H32N6O12S2	613.16	0.82	2.15	↑*		1.32	↑

↓ indicates a decrease; ↑ indicates an increase. ^*P < 0.05