Fig. 4.

Comparison of inter-cluster heterogeneity of scEC-generated clusters versus established annotations. Plots of $H_S(g)$ based on an scEC-generated clustering (x-axis) and established annotations (y-axis) for the a Zheng and b Stumpf, and c an alternative data set from Tian [41, 46, 52]. In all panels each point represents a gene profiled and the red line indicates $H_{\mathit{scEC}}(g)=H_{\mathit{Known}}(g)$. For the genes below the red lines, the scEC clustering is better than the prior annotation at explaining the gene expression heterogeneity as inter-cluster variability, and vice versa for the genes above the red line