Table 3.

The schedule of enrolment, randomisation, assessments and follow-up

Procedure	Screening	Baseline	1 month	2 months	3 months	4 months	5 months	6 months	3 years
Review eligibility criteria	X	X
Written informed consent		X
Demographic data and medical history		X
Questionnaires: KDQoL, EQ-5D-5L, PSQI, SONG-HD, TTR		X	X		X			X
MoCA		X			X			X
Baseline health economics questionnaire		X
Randomisation		X
Intradialytic urine collection and paired blood samples*		X						X
Serum beta-2 microglobulin*		X	X	X	X	X	X	X
Resource use and expenditure questionnaire			X		X			X
Routine clinical data◊ including adherence, dialysis adequacy, blood pressure and monthly blood results		X	X	X	X	X	X	X
Capture of routine clinical data and resource usage (UKRR, SRR, HES, ONS, ISD)									X

*Blood samples drawn at the same time as routine clinical testing. ^◊Routinely collected data on all dialysis units