. 2023 Jun 12;149(12):10685–10700. doi: 10.1007/s00432-023-04949-y

Table 1.

Correlation between the expression of PD-L1, CD86, and CD206 and clinicopathological features in hepatocellular carcinoma

Characteristics	PD-L1 expression				CD86 expression				CD206 expression
Characteristics	Low	High	χ²	P	Low	High	χ²	P	Low	High	χ²	P
Gender
Male	19	27	0.331	0.656	23	23	0.00	1.00	7	39	4.831	0.028
Female	7	7	0.331	0.656	7	7	0.00	1.00	6	8	4.831	0.028
Age
< 60	13	21	0.830	0.362	18	16	0.271	0.602	9	25	1.067	0.302
≥ 60	13	13	0.830	0.362	12	14	0.271	0.602	4	22	1.067	0.302
Tumor size(cm)
< 5	13	16	0.051	0.821	14	15	0.067	0.796	6	23	0.032	0.859
≥ 5	13	18	0.051	0.821	16	15	0.067	0.796	7	24	0.032	0.859
Tumor capsule
Yes	13	16	0.051	0.821	14	15	0.067	0.796	6	23	0.032	0.859
No	13	18	0.051	0.821	16	15	0.067	0.796	7	24	0.032	0.859
Number of tumors
Single	22	24	1.621	0.203	22	24	0.373	0.542	9	37	0.513	0.474
Multiple	4	10	1.621	0.203	8	6	0.373	0.542	4	10	0.513	0.474
Vascular invasion
Yes	5	12	1.872	0.171	9	8	0.082	0.774	5	12	0.838	0.360
No	21	22	1.872	0.171	21	22	0.082	0.774	8	35	0.838	0.360
Portal vein tumor thrombus
Yes	14	16	0.271	0.602	14	16	0.267	0.606	7	23	0.098	0.754
No	12	18	0.271	0.602	16	14	0.267	0.606	6	24	0.098	0.754
Cirrhosis
Yes	15	16	0.667	0.414	15	16	0.067	0.796	6	25	0.202	0.653
No	11	18	0.667	0.414	15	14	0.067	0.796	7	22	0.202	0.653
AFP(ug/L)
< 13.4	16	11	5.287	0.071	14	13	0.085	0.959	6	21	1.852	0.396
13.4 ≤ AFP < 400	7	14			10	11			6	15
≥ 400	3	9			6	6			1	11
Hepatitis
Yes	19	21	0.848	0.357	21	19	0.300	0.584	4	36	9.624	0.002
No	7	13	0.848	0.357	9	11	0.300	0.584	9	11	9.624	0.002
Differentiation degree
Low	5	12	7.855	0.02	7	10	1.744	0.418	5	12	1.075	0.584
Medium	14	21			20	15			6	29
High	7	1			3	5			2	6
AJCC stage
I	14	10	3.716	0.156	11	13	1.217	0.544	3	21	2.111	0.348
II	5	11			7	7			4	12
III	7	13			12	8			6	14

*Statistically significant

The bold values were considered statistically significant