Table 5.
GO and KEGG enrichment analyses of PD-L1 and functional partner genes in hepatocellular carcinoma
| Ontology | ID | Description | P value |
|---|---|---|---|
| BP | GO:0031295 | T cell co-stimulation | 1.15e-13 |
| BP | GO:0031294 | Lymphocyte co-stimulation | 1.28e-13 |
| BP | GO:0050870 | Positive regulation of T cell activation | 1.83e-12 |
| CC | GO:0009897 | External side of plasma membrane | 1.19e-08 |
| CC | GO:0042101 | T cell receptor complex | 3.03e-05 |
| CC | GO:0030136 | Clathrin-coated vesicle | 9.75e-05 |
| MF | GO:1,990,782 | Protein tyrosine kinase binding | 1.64e-05 |
| MF | GO:0015026 | Co-receptor activity | 2.68e-04 |
| MF | GO:0001618 | Virus receptor activity | 7.60e-04 |
| KEGG | hsa04514 | Cell adhesion molecules | 2.86e-09 |
| KEGG | hsa05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer | 1.77e-08 |
| KEGG | hsa04660 | T cell receptor signaling pathway | 3.89e-08 |