Table 1.
Baseline patient characteristics
| GLP-1RA (n=233) | Non-GLP-1RA (n=1574) | |
| Age, years | 60.7 (8.7) | 61.2 (8.6) |
| Sex, No. (%) | ||
| Male | 59 (25.3%) | 429 (27.3%) |
| Female | 174 (74.7%) | 1145 (72.7%) |
| Weight, kg | 66.0 (12.2) | 65.1 (12.3) |
| BMI, kg/m2 | 25.2 (3.7) | 25.1 (3.6) |
| HbA1c, % | 7.3 (1.6) | 7.2 (1.5) |
| Duration of diabetes, years | 8.1 (6.0) | 8.3 (5.8) |
| Duration since initial clinically diagnosed KOA, years | 5.8 (5.8) | 5.5 (5.8) |
| SBP (mmHg) | 129.3 (16.2) | 130.5 (16.4) |
| DBP (mmHg) | 79.5 (10.9) | 80.1 (11.3) |
| Current smoker, No. (%) | 24 (10.3%) | 173 (11.0%) |
| Use antidiabetes agents, No. (%) | ||
| Oral antidiabetes drugs | 218 (93.5%) | 1454 (92.4%) |
| Insulin | 148 (63.5%) | 991 (63.0%) |
| Kellgren-Lawrence grade, No. (%) | ||
| Grade I | 30 (12.9%) | 221 (14.0%) |
| Grade II | 131 (56.2%) | 875 (55.6%) |
| Grade III | 72 (30.9%) | 478 (30.4%) |
| Predominantly lateral KOA, No. (%) | 42 (18.0%) | 298 (18.9%) |
| WOMAC total score | 19.3 (9.7) | 19.8 (9.6) |
| WOMAC pain subscore | 18.3 (13.8) | 17.4 (12.3) |
| WOMAC stiffness subscore | 18.2 (12.1) | 18.3 (15.5) |
| WOMAC function subscore | 19.7 (12.6) | 20.7 (11.9) |
Data are shown as means (SDs) unless otherwise indicated.
WOMAC questionnaire and all its subscales were normalised to scores within a range of 0–100.
BMI, body mass index; DBP, diastolic blood pressure; GLP-1RA, glucagon-like peptide-1 receptor agonist; HbA1c, hemoglobin A1c; KOA, knee osteoarthritis; SBP, systolic blood pressure; WOMAC, Western Ontario and McMaster Universities Osteoarthritis Index.