Table 5.

Before-and-after comparison within the GLP-1RA group

	Pretreatment (n=126)	Post-treatment (n=126)	Mean difference (95% CI)	P value
Annual consumption of oral NSAIDs and acetaminophen, RDD/year	16.8 (14.7)	14.0 (12.2)	2.80 (1.96, 3.62)	<0.001
Annual consumption of topical NSAIDs, RDD/year	24.5 (24.3)	16.6 (19.6)	7.96 (6.27, 9.65)	<0.001
Annual consumption of opioids, MME/year	97.7 (195.1)	93.5 (182.3)	4.17 (−17.52, 25.86)	0.70
Annual no of intra-articular therapies, per year	1.35 (2.67)	0.76 (1.40)	0.59 (0.27, 0.91)	<0.001
Annual no of intra-articular injection of steroids, per year	0.18 (0.41)	0.10 (0.21)	0.082 (0.038, 0.13)	<0.001

GLP-1RA, glucagon-like peptide-1 receptor agonist; MME, morphine milligram equivalent; NSAIDs, non-steroidal anti-inflammatory drugs; RDD, recommended daily dose.