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. 2023 Aug 11;13(8):e073480. doi: 10.1136/bmjopen-2023-073480

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© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Diagram showing numbers of male pleural mesothelioma cases and controls across the years and their main characteristics, Italy, 2000–2018. Cases from all years and areas (analysis A1). In the primary approach, subjects ever employed in non-construction blue-collar occupations for >5 years were excluded; in the secondary approach, all subjects (also those ever employed in non-construction blue-collar occupation for >5 years) were included. CARA, Cholangiocarcinoma Aetiology: Role of Asbestos; EAGLE, Environment And Genetics in Lung cancer Aetiology; MISEM, Multicentre Italian Study on the Aetiology of Mesothelioma; ReNaM, Registro Nazionale Mesoteliomi.