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. 2023 Aug 5;25:100569. doi: 10.1016/j.lana.2023.100569

Table 1.

Opioid-involved overdose deaths by specific drugs with and without synthetic opioids, US, 2014–2019.

2014 2015 2016 2017 2018 2019
# Opioid-involved fatal overdoses (T40.0, T40.1, T40.2, T40.3, T40.4, T40.6) 28,723 33,204 42,435 47,885 47,096 50,179
 #(%) Heroin (T40.1) 10,610 (36.9) 13,051 (39.3) 15,551 (36.6) 15,594 (32.6) 15,102 (32.1) 14,116 (28.1)
 #(%) Heroin (T40.1); no Synthetic Opioid (T40.4) 9581 (33.4) 10,358 (31.2) 9745 (23.0) 7444 (15.5) 5981 (12.7) 5313 (10.6)
 #(%) Prescription Opioid (T40.2) 12,187 (42.4) 12,747 (38.4) 14,534 (34.3) 14,560 (30.4) 12,620 (26.8) 11,942 (23.8)
 #(%) Prescription Opioid (T40.2); no Synthetic Opioid (T40.4) 3181 (11.1) 3030 (9.1) 2828 (6.7) 2423 (5.1) 2138 (4.5) 1775 (3.5)
 #(%) Synthetic Opioid (T40.4) 5561 (19.4) 9610 (28.9) 19,500 (46) 28,660 (59.9) 31,525 (66.9) 36,603 (72.9)
 #(%) Stimulant (T40.5, T43.6) 5023 (17.5) 6634 (20.0) 10,302 (24.3) 14,574 (30.4) 16,314 (34.6) 19,365 (38.6)
 #(%) Cocaine (T40.5) 3431 (11.9) 4529 (13.6) 7321 (17.3) 10,218 (21.3) 10,986 (23.3) 12,108 (24.1)
 #(%) Cocaine (T40.5); no Synthetic Opioid (T40.4) 2798 (9.7) 2979 (9.0) 3101 (7.3) 2906 (6.1) 2253 (4.8) 1875 (3.7)
 #(%) Psychostimulant (T43.6) 1813 (6.3) 2366 (7.1) 3446 (8.1) 5239 (10.9) 6466 (13.7) 8716 (17.4)
 #(%) Psychostimulant (T43.6); no Synthetic Opioid (T40.4) 1536 (5.3) 1871 (5.6) 2398 (5.7) 2678 (5.6) 2831 (6.0) 3106 (6.2)
 #(%) Benzodiazepine (T42.4) 6749 (23.5) 7500 (22.6) 9261 (21.8) 10,038 (21.0) 9166 (19.5) 8330 (16.6)
 #(%) Benzodiazepine (T42.4); no Synthetic Opioid (T40.4) 5523 (19.2) 5699 (17.2) 5946 (14.0) 5150 (10.8) 4082 (8.7) 3125 (6.2)

Notes: Data are from the restricted-use, multiple cause-of-death mortality files from the National Vital Statistics System (NVSS) and cover all 50 states and DC. Drug categories are not mutually exclusive.

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