FIG. 7.

vhs-induced RNA degradation is not influenced by a 3′ poly(A) tail. Internally labeled PPL RNA containing (A) or lacking (B) a ∼35-residue poly(A) tail followed by GU was incubated with RRL vhs (lanes vhs) and RRL control (lanes Retic) for the indicated times (minutes). RNA reaction products were then analyzed by agarose-formaldehyde gel electrophoresis as in Fig. 1. Lanes 1. input, untreated RNAs.