Table 1.

Baseline demographics and clinical characteristics at initial diagnosis.

Characteristic	R/R cohort - all patients (n = 10)
Median age (range), years	13 (9 – 16)
< 18 years	10 (100%)
Male sex	7 (70%)
Initial diagnosis (n)
Classical Hodgkin lymphoma	10
Stage at initial diagnosis
II  III  IV	5 (50%) 2 (20%) 3 (30%)
B-symptoms at initial diagnosis	4 (40%)
Original sites of disease (multiple lymph nodes in 1 region not counted separately)
2  3-5  >5 Lung involvement Bone/marrow involvement	4 (40%) 3 (30%) 3 (30%) 3 (30%) 1 (10%)
Prior systemic therapy
2×OEPA/2×COPDAC  2×OEPA/2×COPDAC/radiation therapy  2×OEPA/2×DECOPDAC  2×OEPA/4×COPDAC  2×OEPA/4×DECOPDAC/radiation therapy  2×OEPA	3 (30%) 1 (10%) 1 (10%) 3 (30%) 1 (10%) 1 (10%)
Initial response to first line therapy
CMR/CR  PMR/PR  Progressive disease	5 (50%) 1 (10%) 4 (40%)
Response status prior to induction therapy
Refractory  Relapsed, 1st relapse  Relapsed, 2nd relapse	4 (40%) 5 (50%) 1 (10%)
Median days (range) between diagnosis of first relapse and last day of initial treatment	176 (8 – 804)
Median performance status (range) at recurrence prior to induction therapy  Karnofsky	100 (80 – 100)