Figure 2.

Macrophage subset analysis

Visually weighted expression of a murine M1 (A) and M2 (B) macrophage gene signature score across the macrophage subset split by treatment groups. (C) Simultaneous visual weighting of both M1 and M2 gene signatures to demonstrate individual cells that have high signal for both gene signatures (yellow), M1 genes (green), M2 genes (red), or neither (gray). (D) Expression of selected tumor-relevant immunomodulatory genes in macrophage subset by cell type. (E) Expression of M1 and M2 genes by scRNA-seq sample.