Figure 7.
Tissues targeted by the RNAi therapeutics
Overall distribution of tissues targeted by the RNAi therapeutics in the published and ongoing clinical trials, from 2008 to 2023 and 2015 to 2023, respectively. The names of the RNAi therapeutics are included in the organ box together with the number of RNAi therapeutics found to target the specific organ in the published and ongoing clinical trials. The color of the border of the organ boxes correlates with the color-coded annotations in Figure 6. The five FDA- and EMA-approved therapeutical RNAi-based drugs are highlighted in bold. Inspired by Hu et al.20 Created using BioRender.com.