Table 2.

Summary of Parameter Estimates from ITT Linear Mixed Models of Number of RBD Episodes Over Time (Baseline, Titration, Final Dose)

Number of RBD episodes	Estimate (SE)	95% CI	t-value	p
Model 1
Intercept	42.8 (4.9)	32.8 to 52.9	8.80	<0.0001
Time × Group = Placebo	−10.5 (6.0)	−22.6 to 1.6	−1.75	0.087
Time × Group = SXB	−23.1 (6.4)	−36.0 to −10.2	−3.62	0.001
Model 2
Intercept	42.8 (4.9)	32.8 to 52.9	8.80	<0.0001
Time	−10.5 (6.0)	−22.6 to 1.6	−1.75	0.087
Time*Group	−12.6 (8.2)	−29.2 to 4.0	−1.53	0.133

CI, confidence interval; ITT, intention-to-treat; RBD, rapid-eye-movement sleep behavior disorder; SXB, sodium oxybate