Table 1.
LMMs Indices in TST, NREM, and REM Sleep
| LMM indices (per hour), median [IQR] Mean LMM duration (seconds), median [IQR] |
TST | NREM | REM | P-values NREM vs. REM; unadjusted adjusted | ES | |
|---|---|---|---|---|---|---|
| Total LMM index | 6.8 (4.5–10.8) | 6.2 (4.3–10.1) | 8.4 (4.4–12.9) | 0.028* | 0.363 | 0.22* |
| Mean duration | 12.3 (10.7–14.4) | 12.7 (11.1–15.2) | 10.4 (8.3–13.2) | <0.001*** | <0.001*** | 0.50** |
| LMM not associated to any event | 0.7 (0.3–1.6) | 0.6 (0.2–1.6) | 0.7 (0–1.8) | 0.390 | 0.850 | 0.07 |
| Mean duration | 6.8 (5.4–8.4) | 6.8 (5.6–8.6) | 5.8 (4.6–7.7) | 0.005* | 0.087 | 0.38** |
| LMM associated with arousals or awakenings | 5.6 (4.1–9.2) | 5.5 (3.7–8.6) | 6.6 (3.9–10.7) | 0.067 | 0.629 | 0.18* |
| Mean duration | 13.3 (11.8–15.2) | 14.0 (11.7–15.8) | 11.6 (8.5–14.4) | <0.001*** | <0.001*** | 0.47** |
| LMM associated with arousals or awakenings, without respiratory events | 5.0 (3.5–8.1) | 5.0 (3.3–8.1) | 5.3 (2.6–8.6) | 0.850 | 0.850 | 0.02 |
| Mean duration | 13.4 (11.8–15.6) | 13.8 (12.0–16.2) | 11.4 (8.5–15.2) | <0.001*** | 0.002** | 0.41** |
| LMM associated with arousals | 3.2 (2.0–5.4) | 3.0 (1.7–5.2) | 3.7 (2.1–7.8) | 0.004** | 0.074 | 0.28* |
| Mean duration | 9.3 (8.4–10.9) | 10.0 (2.2) | 8.2 (6.6–10.9) | <0.001*** | 0.006** | 0.38** |
| LMM associated with arousals, without respiratory events | 2.9 (1.6–4.6) | 2.7 (1.5–4.7) | 2.7 (1.4–5.8) | 0.084 | 0.629 | 0.17* |
| Mean duration | 9.2 (8.1–10.7) | 9.6 (8.2–11.1) | 8.1 (6.5–10.9) | <0.001*** | 0.011* | 0.38** |
| LMM associated with awakenings | 2.4 (−1.9–3.1) | 2.4 (1.7–3.2) | 2.0 (0.9–3.5) | 0.023** | 0.328 | 0.23* |
| Mean duration, mean (SD) | 18.3 (3.8) | 18.5 (4.1) | 16.6 (11.7–20.7) | 0.081 | 0.629 | 0.19* |
| LMM associated with awakenings, without respiratory events | 2.2 (1.8–3.0) | 2.3 (1.6–3.2) | 1.7 (0.7–3.1) | 0.002** | 0.040* | 0.31** |
| Mean duration, mean (SD) | 18.3 (3.8) | 18.5 (4.0) | 16.7 (11.5–20.7) | 0.090 | 0.629 | 0.19* |
| LMM associated with respiratory events | 0.4 (0.1–1.3) | 0.3 (0–0.9) | 0 (0–1.9) | 0.040** | 0.485 | 0.15* |
| Mean duration | 10.8 (8.6–14.0) | 11.3 (9.2–15.2) | 9.6 (3.8) | 0.004** | 0.073 | 0.45** |
| LMM associated with respiratory events, without arousals or awakenings | 0 (0–0.1) | 0 (0–0.1) | 0 (0–0) | 0.169 | 0.850 | 0.29* |
| Mean duration, mean (SD) | 8.1 (3.4) | 8.0 (3.3) | 8.3 (3.5) | 0.705 | 0.835 | 0.18* |
| LMM associated with respiratory events and arousals | 0.3 (0–0.7) | 0.2 (0–0.6) | 0 (0–1.4) | 0.010** | 0.154 | 0.21* |
| Mean duration | 10.7 (8.6–13.7) | 11.3 (8.6–14.8) | 8.5 (5.9–11.8) | 0.064 | 0.629 | 0.31** |
| LMM associated with respiratory events and awakenings | 0 (0–0.1) | 0 (0–0.1) | 0 (0–0) | 0.296 | 0.850 | 0.05 |
| Mean duration, mean (SD) | 17.6 (6.9) | 18.1 (7.7) | 16.7 (9.2) | 0.623 | 0.835 | 0.18* |
The P-value is the represent the significance tested between REM and NREM sleep. Bold* represent significant difference (p < 0.05) or ES > 0.3. One star means p < 0.05 or ES > 0.1, 2 stars means p < 0.01 or ES > 0.3, 3 stars < 0.001or ES > 0.5.
IQR, Interquartile range; LMM, Large muscle group movements; NREM, Non-rapid eye movements; REM, Rapid eye movement.