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. 2023 Jul 20;66(15):10252–10264. doi: 10.1021/acs.jmedchem.3c00161

Figure 2.

Figure 2

In vitro metabolic stability of 30 in liver microsomes. (A) Simulated phase-I metabolic stability of 30 in mouse, rat, and human liver microsomes with diclofenac as the reference. (B) Simulated phase-II metabolic stability of 30 in mouse, rat, and human liver microsomes with diclofenac as reference. Source data are provided in Table S4.