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. 2023 Jul 20;66(15):10252–10264. doi: 10.1021/acs.jmedchem.3c00161

Figure 4.

Figure 4

In vivo evaluation of 30 in a stage-I mouse model of HAT. Survival rate (A) and parasitemia (B) of stage-I T. b. brucei-infected mice treated with vehicle (n = 3), suramin (n = 3) at 10 mg/kg or 30 (n = 3) at 50, 25, 12.5, and 6.25 mg/kg.