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. 2023 Jul 20;66(15):10252–10264. doi: 10.1021/acs.jmedchem.3c00161

Table 6. Pharmacokinetic Parameters of 30.

compound dosing Tmax (h) Cmax (μM) T1/2 (h) AUC0–6h (ng·h/mL) Cl (mL/min)
30 50 mg/kg PO 1 5.25 3.46 6064.75 58.5
  10 mg/kg IP   13.18 1.06 3928.37 171