Table 6. Pharmacokinetic Parameters of 30.
compound | dosing | Tmax (h) | Cmax (μM) | T1/2 (h) | AUC0–6h (ng·h/mL) | Cl (mL/min) |
---|---|---|---|---|---|---|
30 | 50 mg/kg PO | 1 | 5.25 | 3.46 | 6064.75 | 58.5 |
10 mg/kg IP | 13.18 | 1.06 | 3928.37 | 171 |
compound | dosing | Tmax (h) | Cmax (μM) | T1/2 (h) | AUC0–6h (ng·h/mL) | Cl (mL/min) |
---|---|---|---|---|---|---|
30 | 50 mg/kg PO | 1 | 5.25 | 3.46 | 6064.75 | 58.5 |
10 mg/kg IP | 13.18 | 1.06 | 3928.37 | 171 |