. 2023 Jul 24;66(15):10628–10638. doi: 10.1021/acs.jmedchem.3c00775

Table 3. Equilibrium Dissociation Constant (K_D) and Maximum Binding Density (B_max) Values (n = 3; Mean ± SD) of [³H]1 in AD, PSP, CBD, PiD, and PD Brain Homogenates.

radioligand	AD tissue		PSP tissue		CBD tissue		PiD tissue		PD tissue
	K_D (nM)	B_max (nM)	K_D (nM)	B_max (nM)	K_D (nM)	B_max (nM)	K_D (nM)	B_max (nM)	K_D (nM)	B_max (nM)
[³H]1	4.0 ± 3.1	520 ± 370	5.1 ± 1.2	310 ± 90	4.5 ± 0.4	270 ± 40	9.7 ± 7.4	190 ± 100	89 ± 10	140 ± 50

Table 3. Equilibrium Dissociation Constant (KD) and Maximum Binding Density (Bmax) Values (n = 3; Mean ± SD) of [3H]1 in AD, PSP, CBD, PiD, and PD Brain Homogenates.