Table 5. In Vivo PK-Tox Properties of Inhibitor 7k.

assay	result
tolerability p.os 50 mg/kg up to 24 h	no toxic effect (score 0)
PK p.os 50 mg/kg, data points 30, 60, 120, 240, 360 minb NMRI female mice 10 weeks old ENVIGO, formulation: suspension, stabilized with HMC, 0.5%	t1/2 = 53 min
	Tmax = 60 min
	Cmax = 0.064 μg/mL
	AUC0–t = 13.1 μg/mL*min
	AUC0-inf_obs = 13.3 μg/mL*min