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. 2023 Aug 14;12:73. doi: 10.1186/s40249-023-01119-7

Table 5.

Sensitivity analyses accounting for seasonality in the analysis of the impact of treat-all on three indicators of ART among PLHIV in China 1 January 2015 to 31 December 2019#

IRR (95% CI)
Level change at treat-all P value Level change in
December 2019
P value Trend before treat-all P value Trend after treat-all P value
Proportion of 30-day ART initiation* 1.116 (1.057–1.179)  < 0.001 1.006 (0.727–1.394) 0.969 1.011 (1.004–1.017) 0.002 1.008 (1.007–1.009)  < 0.001
Mean CD4 0.996 (0.995–1.038) 0.844 1.002 (0.876–1.146) 0.979 0.997 (0.995–1.000) 0.056 0.997 (0.997–0.998)  < 0.001
Mean estimated time to diagnosis 1.070 (1.024–1.118) 0.002 0.970 (0.856–1.099) 0.646 1.004 (1.001–1.006) 0.002 1.001 (1.000–1.003) 0.043

IRR Incidence rate ratio, CI Confidence interval, ART Antiretroviral therapy. Treat-all: June 2016. PLHIV: People living with HIV. #: three indicators include proportion of 30-day ART initiation, mean CD4 counts (cells/μL) at ART initiation, and mean estimated time from infection to diagnosis (year). *: using quasi-Poisson segmented regression models. †: using Poisson segmented regression models