Table 5.
Associations between gender identity and number of mental health diagnoses with self-inflicted injury using a common referent approach among TM and matched cisgender youth included in the STRONG cohort
| TF and CM cohort | TF and CF cohort | |||||
|---|---|---|---|---|---|---|
| # of events/total | % | PR (95% CI) | # of events/total | % | PR (95% CI) | |
|
| ||||||
| Cisgender, 0 diagnoses | 64/10363 | 0.6% | ref | 83/10386 | 0.8% | ref |
| Cisgender, 1–2 diagnoses | 62/2822 | 2.2% | 3.5 (2.5, 5.1) | 99/2912 | 3.4% | 4.8 (3.5, 6.5) |
| 49/773 | 6.3% | 102/690 | 15% | 22.7 (16.2, 31.8) | ||
| Cisgender, 3+ diagnoses | 9.9 (6.6, 14.8) | |||||
| TM, 0 diagnoses | 21/666 | 3.2% | 5.2 (3.2, 8.5) | 21/666 | 3.2% | 3.8 (2.4, 6.2) |
| 69/492 | 14% | 21.1 (14.4, 31.0) | 69/492 | 14% | 19.6 (13.7, 28.1) | |
| TM, 1–2 diagnoses | ||||||
| TM, 3+ diagnoses | 74/273 | 27% | 46.6 (30.6, 70.9) | 74/273 | 27% | 35.5 (23.6, 53.5) |
|
| ||||||
| Magnitude of additive interaction (RERI)a between TF status and 1–2 mental health diagnoses | 13.4 (observed PR=21.1, expected PR=7.8) | 10.0 (observed PR=19.6, expected PR=7.6) | ||||
| Magnitude of additive interaction (RERI)a between TF status and 3+ mental health diagnoses | 32.5 (observed PR=46.6, expected PR=14.1) | 10.0 (observed PR=35.5, expected PR=25.6) | ||||
| Magnitude of multiplicative interaction (MIR)a between TF status and 1–2 mental health diagnoses | 1.1 (observed PR=21.1, expected PR=18.4) | 1.1 (observed PR=19.6, expected PR=18.3) | ||||
| Magnitude of multiplicative interaction (MIR)a between TF status and 3+ mental health diagnoses | 0.9 (observed PR=46.6, expected PR=51.8) | 0.4 (observed PR=35.5, expecte PR=87.2) | ||||
PR = prevalence ratio; CI = confidence interval; TM – transmasculine; CF = cisgender female; CM = cisgender male; RERI = relative excess risk due to interaction; MIR=multiplicative interaction ratio
a
Values obtained from a model, which accounts for matched study design; minor differences may appear due to rounding.