FIG. 7.

RCMV is attenuated upon deletion of the R78 gene. REF were infected at an MOI of 0.01 with either wt RCMV (○), RCMVΔR78a (■), or RCMVΔR78c (●). RSMC were infected with wt and mutant virus at an MOI of 1 (relative to REF infection). The upper graphs show the infected cell/total cell ratios at various time points p.i.; the lower graphs show virus titers determined in culture medium up to 7 days p.i. Standard deviations are indicated by vertical bars.