Table 1.
General features and lesion volume in patients with hypothalamic hamartoma according to Delalande and Fohlen classifications.
| F/M(N) | DF‐I | DF‐II | DF‐III | DF‐IV | Total | p |
|---|---|---|---|---|---|---|
| 8/7 | 7/23 | 9/19 | 1/4 | 25/53 | ns | |
| Age at onset (years, mean ± SD) | 12.12 ± 7.17 | 2.29 ± 2.34 | 1.54 ± 1.53 | 0.75 ± 0.78 | 3.81 ± 5.39 | p < 0.001 |
| Age at evaluation (years, mean ± SD) | 17.95 ± 9.47 | 10.38 ± 8.11 | 5.67 ± 6.00 | 7.05 ± 5.84 | 9.93 ± 8.67 | p < 0.001 |
| Disease duration (years, mean ± SD) | 5.83 ± 6.37 | 8.09 ± 7.02 | 4.13 ± 5.66 | 6.29 ± 5.92 | 6.12 ± 6.47 | ns |
| Precocious puberty (N) | 2 | 2 | 8 | 4 | 16 | p = 0.002 |
| GS (N, onset age) | 4 (11.00 ± 12.43) | 26 (2.24 ± 2.24) | 25 (1.36 ± 1.37) | 4 (0.90 ± 0.82) | 59 (2.37 ± 4.11) | p < 0.001 |
| Non‐GS (N, onset age) | 15 (12.87 ± 7.46) | 21 (7.75 ± 4.89) | 20 (3.96 ± 3.29) | 4 (5.99 ± 6.46) | 60 (7.65 ± 6.22) | p < 0.001 |
| Total volume of HH (mm3) | 1286.00 ± 1291.91 | 270.00 ± 142.49 | 2057.86 ± 1504.84 | 15040.00 ± 5282.38 | 2053.97 ± 3854.87 | p < 0.001 |
| Volume of intraventricular HH (mm3) | NA | 270.00 ± 142.49 | 786.07 ± 566.96 | NA | 519.14 ± 479.84 | p < 0.001 |
DF, Delalande and Fohlen classifications; F, female; M, male; GS, gelastic seizures; HH, hypothalamic hamartoma.