Table 1.

Somatic variants obtained from the WGS bioinformatic analysis.

GENE	CHR	POSITION	REF	ALT	HGVS.c	HGVS.p	COVERAGE	ALLELE COVERAGE	FREQUENCY	CLINVAR	CLINVAR STATUS	CANCERVAR	gnomAD	CADD
PIK3CA	chr3	179234297	A	G	c.3140A>G	p.His1047Arg	120	79,41	34.17 %	Pathogenic	3	Tier_II_potential [10]	.	22.5
TP53	chr17	7675088	C	T	c.524G>A	p.Arg175His	70	31,39	55.71 %	Pathogenic	2	Tier_I_strong [11]	1.548e-05	23.4
NFKB2	chr10	102400117	G	CLI	c.1507G>C	p.Val503Leu	68	35,33	48.53 %	.	-1	Tier_III_Uncertain [3]	.	23.7
ATM	chr11	108312478	G	C	c.5986G>C	p.Glu1996Gln	106	58,48	45.28 %	.	-1	Tier_II_potential [8]	.	24.1