Figure 8. Significantly different expression profiles across time points following challenge.
(A) For participants vaccinated with ViPS, a representative example gene from each cluster is plotted. Regression fit curves are shown for each group. An expression profile of these genes for ViTT recipients is also shown as a reference. (B) For participants vaccinated with ViTT. a representative example gene from each cluster is plotted. Regression fit curves are shown for each group. An expression profile of these genes for ViPS recipients is also shown as a reference. (C) Overlap between the significantly expressed genes in ViPS and ViTT vaccination groups compared with control. (D) Significantly enriched GO terms (biological process) among 323 genes with significantly different expression profiles for the ViTT-vaccinated group but not the ViPS-vaccinated group.