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. 2023 Jul 31;14:1189278. doi: 10.3389/fneur.2023.1189278

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Copyright © 2023 Gouilly, Salabert, Bertrand, Goubeaud, Catala, Germain, Ainaoui, Rafiq, Benaiteau, Carlier, Nogueira, Planton, Hitzel, Méligne, Sarton, Silva, Lemesle, Payoux, Thalamas, Péran and Pariente.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Inter-individual heterogeneity of the relationship between cognitive performances and SUVR values. (Panel A) represents the relationship between the MMS score and the whole brain SUVR. (Panel B) shows the relationship between the 7-day total recall on the FCSRT and the temporal meta-ROI SUVR. To facilitate comparisons between the distribution of cognitive scores and SUVR values, we calculated z-scores based on the present population (i.e., a null z-value corresponds to the mean of the study cohort). Each line represents one AD patient (MAB or HAB). The reference region was the CC for the whole brain SUVR (panel A) and the WB for the temporal meta-ROI (panel B). CC: cerebellar cortex; FCSRT: free and cued selective reminding test; MMS: mini-mental state examination; ROI: region of interest; SUVR: standard uptake value ratio; WB: whole brain.