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. 2023 Aug 14;13:280. doi: 10.1038/s41398-023-02573-5

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A Experimental protocol. B HSPA12A expression. After ASS, the indicated tissues were collected for immunoblotting against HSPA12A. The blots against GAPDH served as loading controls. n = 7/group. C Brief illustration of glycolysis pathway. D Glycolysis-related gene expression. After ASS, the indicated gene expression was analyzed in hippocampus by immunoblotting analysis. n = 5/group. E Lactate in cerebrospinal fluid (CSF). After ASS, CSF was extracted from the mice for lactate content measurement. n = 5/group. Data are mean ± SD, **P < 0.01 and *P < 0.05 by Student’s two-tailed unpaired t test or Mann–Whitney U test.