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. 2023 Feb 22;71(4):505–515. doi: 10.1007/s12026-023-09366-4

Table 1.

Baseline characteristics of the included RCTs in the meta-analysis

Author, year Therapeutic schedule Average age (years) Male Duration of PsA, years PASI score (0–72) Swollen joint count (0–66) Tender joint count (0–68)
Deodhar, Atul 2018 Guselkumab 100 mg at week 0, week 4, and every 8 weeks 47 52% 7.0 ± 7.2 12.0 ± 10.5 11.9 ± 7.6 20.7 ± 12.2
Placebo 44 24% 6.9 ± 7.2 9.9 ± 8.0 10.6 ± 7.5 20.1 ± 12.5
Mease, Philip J. 2020 Guselkumab 100 mg every 4 weeks 46 58% 5.5 ± 5.9 10.8 ± 11.7 12.9 ± 7.8 22.4 ± 13.5
Guselkumab 100 mg at weeks 0, 4, then every 8 weeks 45 52% 5.1 ± 5.5 9.7 ± 11.7 11.7 ± 6.8 19.8 ± 11.9
Placebo 46 48% 5.8 ± 5.6 9.3 ± 9.8 12.3 ± 6.9 21.6 ± 13.1
Coates, L. C. 2022 Guselkumab 100 mg week 0, week 4, then every 8 weeks 49 46% 8.3 ± 7.8 11.7 ± 11.9 10.0 ± 7.0 21.0 ± 13.0
Placebo 49 54% 8.7 ± 7.2 9.2 ± 9.4 9.0 ± 6.0 18.0 ± 11.0
Kristensen, L. E. 2022 Risankizumab 150mg at weeks 0, 4 and 16 52 52% 7.1 ± 7.0 10.9 ± 10.1 12.1 ± 7.8 20.8 ± 14.1
Placebo 52 49% 7.1 ± 7.7 10.0 ± 10.4 12.2 ± 8.0 20.5 ± 12.8
Ostor, A. 2022 Risankizumab 150mg at weeks 0, 4 and 16 53 45% 8.2 ± 8.2 7.7 ± 6.7 13.0 ± 8.7 22.8 ± 14.9
Placebo 52 45% 8.2 ± 8.3 8.4 ± 9.9 13.6 ± 9.0 22.3 ± 13.8
Philip J Mease 2021 Tildrakizumab 200 mg every 4 weeks 50 41% 7.5 ± 8.5 7.6 ± 9.8 10.4 ± 7.4 16.6 ± 11.9
Tildrakizumab 200 mg every 12 weeks 49 53% 6.2 ± 7.2 6.2 ± 7.4 10.0 ± 8.0 19.5 ± 13.9
Tildrakizumab 100 mg every 12 weeks 49 39% 7.0 ± 6.6 8.8 ± 9.5 11.0 ± 8.2 21.3 ± 14.8
Tildrakizumab 20 mg every 12 weeks 47 47% 6.6 ± 6.7 5.5 ± 2.1 9.4 ± 6.4 19.0 ± 13.0
Placebo 48 44% 6.3 ± 6.1 5.0 ± 6.5 11.8 ± 9.8 19.7 ± 14.7

RCT, randomized controlled trial; PsA, psoriatic arthritis; PASI, Psoriasis Area Severity Index