Table 4.

Summary of SNP – SNP interactions on the risk of colorectal cancer analyzed through MDR method.

Model	Training Bal. Acc. ( % )	Testing Bal. Acc. ( % )	CVC	OR (95% CI)	p
rs12412320	0.54	0.54	10/10	1.40 ( 1.13, 1.75 )	0.0025
rs12412320, rs11245008	0.54	0.53	5/10	1.42 ( 1.14, 1.77 )	0.0015
rs12412320, rs11245007, rs11245008	0.55	0.53	10/10	1.48 ( 1.20, 1.84 )	0.0003

MDR, multifactor dimensionality reduction; Bal. Acc., balanced accuracy; CVC, cross–validation consistency; OR, odds ratio; CI, confidence interval.

p values were calculated using Chi-square test, two sided.

Bold indicates statistical significance at P < 0.05.