Table 2.
-Allele change (frequency) of the nucleotide-binding oligomerization domain-like receptor pyrin domain-containing 3 rs35829419 single-nucleotide polymorphism among type 2 diabetes mellitus and control group.
| SNP | Total (n=546) | T2DM (n=271) | Control (n=275) | HWE’s P-value | OR (95% CI) | P-values* |
|---|---|---|---|---|---|---|
| CC | 494 (90.5) | 237 (87.4) | 257 (93.5) | 0.575 | 1.00 | - |
| CA | 51 (9.3) | 33 (12.2) | 18 (6.5) | 1.99 (1.11-3.61) | 0.027 | |
| AA | 1 (0.2) | 1 (0.4) | 0 (0.0) | NA | NA | |
| CA+AA | 52 (9.5) | 34 (12.5) | 18 (6.5) | 2.05 (1.16-3.75) | 0.019 | |
| C | 1039 (95.1) | 507 (93.5) | 532 (96.7) | 1.00 | - | |
| A | 53 (4.9) | 35 (6.5) | 18 (3.3) | 2.04 (1.15-3.70) | 0.016 |
Values are presented as numbers and precentages (%). *Fisher exact test. SNP: single-nucleotide polymorphism, T2DM: type 2 diabetes mellitus, HWE: Hardy-Weinberg equilibrium, OR: odds ratio, CI: confidence interval, NA: not available