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. 2023 May 26;29(16):3142–3150. doi: 10.1158/1078-0432.CCR-23-0396

Figure 5.

Figure 5. Response prediction for a progressive patient. A, Second assessment response prediction. The clinical volume observation showed stable disease at day 91. Prediction 1 shows that insomnia decreased from 3 to 2 at day 28, such that , correctly predicting stable disease. Insomnia continued to decrease, such that , correctly predicting stable disease for predictions 2 through 4. B, Third assessment response prediction. The clinical volume observation showed progressive disease at day 136. Insomnia increased from 1 to 2 at day 101, correctly predicting progressive disease 35 days before it was assessed via volumetric scan on day 136.

Response prediction for a progressive patient. A, Second assessment response prediction. The clinical volume observation showed stable disease at day 91. Prediction 1 shows that insomnia decreased from 3 to 2 at day 28, such that Inline graphic, correctly predicting stable disease. Insomnia continued to decrease, such that Inline graphic, correctly predicting stable disease for predictions 2 through 4. B, Third assessment response prediction. The clinical volume observation showed progressive disease at day 136. Insomnia increased from 1 to 2 at day 101, correctly predicting progressive disease 35 days before it was assessed via volumetric scan on day 136.