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. Author manuscript; available in PMC: 2024 Feb 1.
Published in final edited form as: Maturitas. 2022 Nov 4;168:13–19. doi: 10.1016/j.maturitas.2022.10.006

Figure 3:

Figure 3:

The effect of adrenal function changes with aging on immunomodulation

Elevated cortisol levels that occur with aging have been shown to alter T-cell trafficking, monocyte and T cell apoptosis and thymic involution, whereas the decrease that is seen the DHEAS levels with aging can lead to altered secretion of interleukins, including IL-2 and IL-6 (Figure created in biorender.com)