Table 1. Mean Values and Standard Deviation of the Experimental Data Obtained for the Physicochemical Characterization of Tf-Conjugated and Nonconjugated TMZ+BTZ-PLGA NPs (n = 3).

	TMZ+BTZ loaded PLGA NPs
	nonmodified NPs	Tf-modified NPs
mean diameter (nm)	159 ± 6	156 ± 3
PDI	0.055 ± 0.007	0.042 ± 0.016
ζ potential (mV)	–20.5 ± 1.5	–21.5 ± 1.6
EE TMZ (%)	65.4 ± 15.8	60.1 ± 8.8
EE BTZ (%)	71.1 ± 12.2	49.8 ± 12.3
TMZ LC (%)	1.7 ± 0.1	1.6 ± 0.3
BTZ LC (%)	1.9 ± 0.3	1.3 ± 0.3