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. 2023 Aug 15;3(8):e0001861. doi: 10.1371/journal.pgph.0001861

Table 2. Input costs of Histoplasma antigen screening and treatment.

Average Cost (USD) References, notes
Histoplasma antigen testing $5·40 [16]
Histoplasma microscopy and fungal culture $56·19 Micro-costing (see Methods)
Itraconazole 100 mg tablet $0·28 Micro-costing (see Methods)
Itraconazole 200 mg twice daily x 14 days $15·68
Amphotericin deoxycholate 50 mg $12·84 [16]
Amphotericin 1mg/kg daily x 14 days $179·76 Assumes a 50 kg patient
Hospitalization (21 days)
    Total 14-day treatment course: Amphotericin + Itraconazole $195·41 See above
    Hospital stay $1,386·77 [31]
    Laboratory testing $62·25 Micro-costing (see Methods)
    Hospital supplies $237·38 Micro-costing (see Methods)
    Chest x-ray $11·38 Micro-costing (see Methods)
    Personnel $27·50 Micro-costing (see Methods)
    Total cost of hospitalization $1,920·68
Post hospitalization itraconazole $380·80 11.5 months of itraconazole
Outpatient management of histoplasmosis 35·06 30-day costs include laboratory monitoring, chest x-ray, clinic personnel. Excludes itraconazole. Micro-costing (see Methods)