Figure 1.

Translating biomarker measurements from laboratories to the operating room: Fundamental research and method development (left), include initial marker discovery, development of a fluorometric assay by using one of four approaches, device engineering, and calibration, and validation by using independent analytical techniques. The benefits for clinical practice and research (right) involve organ assessment and patient monitoring, either for improved patient care or to gather more data for clinical research. We developed a portable spectrofluorometric device for real‐time measurements of biomarkers (center). The spectrometer and light source are connected to tubing carrying perfusate or dialysate and data can be tracked on a mobile application or computer graphical interface.