Extended Data Fig. 1. ROC analysis for discriminating LB positive versus LB negative participants using the Smell test.

At the highest Youden index (−0.9 z-score on the smell test), the sensitivity was 63% and the specificity 86% with an overall percent correctly classified of 85%. Of those with available Smell test score (n = 398), 371 were LB- and 27 LB+.