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Longitudinal association between pathology and clinical outcome
Linear mixed-effects (LME) models examining the interaction between pathology and time (years) using cognition as outcome. Basic models included the interaction between time and LB pathology, age, sex and years of education, as well as a random slope and intercept. At the second step, Aβ was added to the model and at the third step tau. The third model is thus the same as shown in Fig. 3d–f.
