Extended Data Fig. 8. Expansion and persistence of gavo-cel in peripheral blood.
a, Kinetics of gavo-cel T cell expansion and persistence in peripheral blood by qPCR-based detection of specific TRuC-encoding proviral sequences in genomic DNA. Patients are grouped by dose level. b, Gavo-cel expansion and persistence over time in peripheral blood and at specific time points in cancerous tissues. Pink squares denote gavo-cel transgene level in serosal effusion; green circle denotes gavo-cel transgene level in peritoneal mesothelioma nodule. *Partial response by local investigator assessment.