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. 2023 Jul 27;29(8):2099–2109. doi: 10.1038/s41591-023-02452-y

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© This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2023, corrected publication 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 2 — a–b, Volumetric and Metabolic Response to gavo-cel treatment. a, Volumetric analysis. Maximum reduction of sum of volumes of target lesions post gavo-cel infusion. b, Metabolic response analysis. Maximum reduction of standardized uptake value (SUV) of the target lesion with the highest SUV assessed at the baseline visit (that is prior to gavo-cel infusion). c, Baseline target lesion volume and response to gavo-cel treatment. Baseline target lesion volume does not correlate with radiological response assessment. The p values were calculated using the Kruskal-Wallis test for n = 29 patients who were treated with gavo-cel.