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. 2023 Jul 24;29(8):1947–1953. doi: 10.1038/s41591-023-02455-9

Table 3.

EDE subscale scores over time and changes from baseline scores

n = 10 Visit Mean (s.d.) 95% CI of mean difference P value Effect size (Cohen’s d)
Restraint Day −1 2.18 (1.76)
1-month f/u 1.38 (1.56) −1.81, 0.21 0.107 0.57
3-month f/u 1.46 (1.84) −1.81, 0.37 0.169 0.47
Eating concern Day −1 2.10 (1.75)
1-month f/u 1.24 (1.50) −1.83, 0.11 0.075 0.64
3-month f/u 1.00 (1.32) −2.20, 0.00 0.051 0.71
Shape concern Day −1 3.68 (1.30)
1-month f/u 2.43 (1.84) −2.40, −0.10 0.036 0.78
3-month f/u 2.43 (1.95) −2.69, 0.19 0.081 0.62
Weight concern Day −1 3.64 (1.65)
1-month f/u 2.76 (1.81) −1.69, −0.07 0.036 0.78
3-month f/u 2.3 (2.00) −2.57, −0.11 0.036 0.78

Subscales are calculated from the EDE. Day −1 is the day before psilocybin dosing session. Effect size was calculated using Cohen’s d. Analysis was performed using a two-sided 5% paired t-test with null hypothesis of no difference between baseline and post-baseline values.

CI, confidence interval; f/u, follow-up.