Table 1.
Females (n = 2019) |
Males (n = 1652) |
P value | |
---|---|---|---|
Baseline characteristics | |||
Age (year) | 57.8 ± 5.7 | 58.1 ± 5.8 | 0.092 |
Height (cm) | 162.8 ± 6.0 | 176.1 ± 6.6 | <0.001 |
Body mass (kg) | 73.6 ± 14.0 | 88.1 ± 13.2 | <0.001 |
BMI (kg/m2) | 27.7 ± 5.2 | 28.3 ± 3.9 | <0.001 |
White (%) | 98.8 | 99.4 | 0.066 |
Physical activity level (%) | |||
Low | 25.2 | 20.2 | <0.001 |
Medium | 35.7 | 25.1 | |
High | 39.2 | 54.7 | |
Sitting (hours/day) | 4.4 ± 2.5 | 4.8 ± 2.6 | <0.001 |
Alcohol (glasses/week) | 7.0 ± 8.3 | 16.9 ± 15.4 | <0.001 |
Smoking (%) | |||
Never | 52.1 | 44.4 | <0.001 |
Previous | 40.6 | 47.2 | |
Current | 7.3 | 8.5 | |
TAFE, college or university education (%) | 52.7 | 50.1 | 0.113 |
Calcium supplementation (%) | 9.3 | 1.2 | <0.001 |
Menopausal hormone therapy (%) | 8.9 | - | - |
Serum 25OHD (nmol/L) | 78.9 ± 25.3 | 85.7 ± 26.1 | <0.001 |
Baseline DXA measures | |||
Fat body mass (kg) | 29.8 ± 10.4 | 25.9 ± 8.4 | <0.001 |
Lean body mass (kg) | 41.4 ± 5.0 | 59.0 ± 6.7 | <0.001 |
Total hip BMD (g/cm2) | 0.988 ± 0.142 | 1.100 ± 0.144 | <0.001 |
Femoral neck BMD (g/cm2) | 0.945 ± 0.136 | 1.017 ± 0.133 | <0.001 |
Lumbar spine BMD (g/cm2) | 1.166 ± 0.176 | 1.270 ± 0.192 | <0.001 |
Changes over 6 years | |||
Measurement interval (year) | 6.2 ± 0.9 | 6.2 ± 0.9 | 0.941 |
∆Total mass (kg) | 0.263 ± 5.711 | 0.076 ± 5.181 | 0.301 |
∆Fat mass (kg) | 0.654 ± 4.685 | 0.616 ± 4.170 | 0.795 |
∆Lean mass (kg) | -0.318 ± 1.791 | -0.566 ± 2.085 | <0.001 |
∆Total hip BMD (g/cm2) | -0.043 ± 0.048 | -0.012 ± 0.038 | <0.001 |
∆Femoral neck BMD (g/cm2) | -0.046 ± 0.050 | -0.016 ± 0.045 | <0.001 |
∆Lumbar spine BMD (g/cm2) | -0.035 ± 0.072 | 0.032 ± 0.061 | <0.001 |
Values are mean ± SD or percentage (%) as stated. 25OHD, 25-hydroxyvitamin D; BMI, body mass index; BMD, bone mineral density. P values obtained using Student’s t-test or chi-square test