Fig. 3.

HRQoL scales used in the included studies. HRQoL scales used to measure HRQoL in achondroplasia. Nineteen different instruments were used to elicit HRQoL data. The most commonly used scale was the QoLISSY questionnaire (n = 5 studies), followed by PedsQL and the SF-36 (n = 4 studies), WeeFIM (n = 3 studies), BPI and KIDSCREEN (n = 2 studies). Other scales were used in one study each, including two studies that assessed utilities (via EQ-5D and 15D scales). The figure does not tally with the number of included studies (N = 18) because of some studies using multiple QoL scales. 15D 15-dimensional measure of health-related quality of life, AAOS American Academy of Orthopaedic Surgeons, APLES Achondroplasia Personal Life Experience Scale, APPT Adolescent Pediatric Pain Tool, BPI Brief Pain Inventory, EQ-5D-5L EuroQol 5-Dimension 5-Level, NHP Nottingham Health Profile, PedsQL Pediatric Quality of Life Inventory, QLI Quality of Life Index, QoLISSY Quality of Life in Short Stature Youth, SDQ Strengths and Difficulties Questionnaire, SF-36 Short Form 36, WeeFIM Functional Independence Measure for Children, WHOQOL-BREF World Health Organization Quality of Life: Brief Version