Table 1.
Distribution of subjects in BU-ADRC Hippocampus data including clinical and neuropathological measurement
| Distribution of subjects in BU Hippocampus data (n=207) | |||||
|---|---|---|---|---|---|
| Variable | AD_pure | AD+VaD | AD+LBD | AD other | Control |
| N | 79 | 56 | 47 | 4 | 21 |
| Age(yr) (SD) | 76.9 (8.30) | 84.6 (9.70) | 79.9 (5.85) | 80.3 (5.56) | 89.0 (9.00) |
| Female N (%) | 12 (15.19) | 17 (30.36) | 7 (14.89) | 0 (0) | 10 (47.62) |
| RIN | |||||
| ≤4.3 | 24 | 12 | 12 | 2 | 4 |
| 4.3<x≤5.6 | 18 | 19 | 14 | 1 | 1 |
| 5.6<x≤6.9 | 16 | 14 | 14 | 1 | 5 |
| >6.9 | 21 | 11 | 7 | 0 | 11 |
| CDR | |||||
| 0 | 0 | 0 | 1 | 9 | 0 |
| 0.5 | 1 | 0 | 2 | 3 | 0 |
| 1 | 1 | 1 | 5 | 2 | 0 |
| 2 | 1 | 3 | 11 | 0 | 0 |
| 3 | 30 | 16 | 30 | 3 | 0 |
| Braak | |||||
| 1 | 0 | 0 | 0 | 0 | 4 |
| 2 | 0 | 0 | 0 | 0 | 11 |
| 3 | 1 | 3 | 2 | 0 | 5 |
| 4 | 3 | 5 | 5 | 3 | 0 |
| 5 | 26 | 21 | 17 | 1 | 1 |
| 6 | 49 | 27 | 23 | 0 | 0 |
| CERAD | |||||
| 0 | 0 | 0 | 0 | 0 | 0 |
| 1 | 70 | 46 | 39 | 3 | 2 |
| 2 | 7 | 7 | 8 | 1 | 2 |
| 3 | 2 | 3 | 0 | 0 | 8 |
| 4 | 0 | 0 | 0 | 0 | 9 |
N: sample size; RIN: RNA integrity number; SD: standard deviation. Values for Age and RIN are expressed as Mean ± SD. AD other was defined as the AD patients not defined as pure AD, AD+VaD, or AD+LBD.