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. Author manuscript; available in PMC: 2023 Oct 23.
Published in final edited form as: Nat Biotechnol. 2023 Feb 16;41(10):1474–1482. doi: 10.1038/s41587-023-01662-6

Figure 2. Continuity of assembled CHM13 chromosomes.

Figure 2.

The minimum number of continuous alignments needed to cover 85% of each chromosome (LGA85) is represented by the number of dashes, or plain numbers when ≥5. Higher numbers are shaded progressively darker. Alignments were taken from QUAST output versus the CHM13v1.1 reference, after filtering errors at heterozygous sites and potential erroneous regions in the reference as in Table 1. Verkko using HiFi data alone is comparable to other HiFi-based assemblies 9,15, but Verkko combining HiFi and ONT data has the most complete and correct chromosomes (12).