Table 1. Demographic and Clinical Characteristics of Infants Admitted to the Intensive Care or High Acuity Unit With Respiratory Syncytial Virus Infection.
| Characteristic | Infants, No. (%) | P valuea | ||
|---|---|---|---|---|
| All (N = 600) | Nonintubated (n = 457) | Intubated (n = 143) | ||
| Age, median (IQR), mo | 2.6 (1.4-6.0) | 3.1 (1.6-6.4) | 1.9 (1.0-3.2) | <.001 |
| Age group | ||||
| 0-2 mos | 323 (53.8) | 222 (48.6) | 101 (70.6) | <.001 |
| 3-5 mos | 127 (21.2) | 106 (23.2) | 21 (14.7) | |
| 6-11 mos | 150 (25.0) | 129 (28.2) | 21 (14.7) | |
| Sex | ||||
| Male | 361 (60.2) | 277 (60.6) | 84 (58.7) | .69 |
| Female | 239 (39.8) | 180 (39.4) | 59 (41.3) | |
| Race and ethnicity | ||||
| Hispanic | 135 (22.5) | 102 (22.3) | 33 (23.1) | NA |
| Non-Hispanic Asian | 13 (2.2) | 11 (2.4) | 2 (1.4) | |
| Non-Hispanic Black | 95 (15.8) | 75 (16.4) | 20 (14.0) | |
| Non-Hispanic White | 265 (44.2) | 199 (43.5) | 66 (46.2) | |
| Multiple or otherb | 30 (5.0) | 21 (4.6) | 9 (6.3) | |
| Unknown | 62 (10.3) | 49 (10.7) | 13 (9.1) | |
| SVI score, median (IQR)c | 0.50 (0.39-0.64) | 0.50 (0.40-0.64) | 0.50 (0.38-0.65) | .98 |
| Insurance | ||||
| Public | 336 (56.0) | 242 (53.0) | 94 (65.7) | .050 |
| Private | 240 (40.0) | 196 (42.9) | 44 (30.8) | |
| Self-pay | 11 (1.8) | 9 (2.0) | 2 (1.4) | |
| Other or unknown | 13 (2.2) | 10 (2.2) | 3 (2.1) | |
| Prematurityd | 169 (28.9) | 116 (26.1) | 53 (37.5) | .01 |
| Gestational age, median (IQR)e | 34.0 (32.0-35.7) | 34.0 (32.4-35.7) | 34.0 (32.0-35.4) | .91 |
| Multiple pregnancyf | 28 (4.7) | 16 (3.5) | 12 (8.4) | .18 |
| Underlying conditions | ||||
| None | 487 (81.2) | 364 (79.6) | 123 (86.0) | .07 |
| At least one | 113 (18.8) | 93 (20.4) | 20 (14.0) | |
| Nonrespiratory, noncardiac | 48 (8.0) | 46 (10.1) | 2 (1.4) | <.001 |
| Cardiac, nonrespiratory | 20 (3.3) | 15 (3.3) | 5 (3.5) | .90 |
| Respiratory | 45 (7.5) | 32 (7.0) | 13 (9.1) | .41 |
| Chronic lung disease | 22 (3.7) | 14 (3.1) | 8 (5.6) | .16 |
| Neurologic | 13 (2.2) | 9 (2.0) | 4 (2.8) | .52 |
| Trisomy 21 | 8 (1.3) | 8 (1.8) | 0 | .21 |
| Reason for admission | ||||
| LRTI | 594 (99.0) | 453 (99.1) | 141 (98.6) | .58 |
| Apnea or bradycardia | 77 (12.8) | 36 (7.9) | 41 (28.7) | <.001 |
| Cardiac arrest at home with CPR | 3 (0.5) | 1 (0.2) | 2 (1.4) | .14 |
| CNS infection | 2 (0.3) | 0 | 2 (1.4) | .06 |
| Shock requiring vasopressors | 5 (0.8) | 0 | 5 (3.5) | .001 |
| Site region | ||||
| Northeast | 146 (24.3) | 125 (27.4) | 21 (14.7) | <.001 |
| Midwest | 145 (24.2) | 92 (20.1) | 53 (37.1) | |
| South | 154 (25.7) | 112 (24.5) | 42 (29.4) | |
| West | 155 (25.8) | 128 (28.0) | 27 (18.9) | |
Abbreviations: CNS, central nervous system; CPR, cardiopulmonary resuscitation; LRTI, lower respiratory tract infection; NA, not applicable; SVI, social vulnerability index.
a
Fisher exact test performed if any expected cell count was less than 5.
b
Multiple or other race and ethnicity group included infants who were of multiple races or were classified as Native Hawaiian/Pacific Islander or American Indian/Alaskan Native.
c
A total of 598 observations.
d
Denominator was for infants with documented prematurity status (total of 585 observations).
e
Gestational age provided for infants born at less than 37 weeks’ gestation.
f
Multiple pregnancy status was collected only for 320 infants aged less than 90 days.